Cell packing influences planar cell polarity signaling

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Cell packing influences planar cell polarity signaling.

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Epithelial cells and other groups of cells acquire a polarity orthogonal to their apical-basal axes, referred to as Planar Cell Polarity (PCP). The process by which these cells become polarized requires a signaling pathway using Frizzled as a receptor. Responding cells sense cues from their environment that provide directional information, and they translate this information into cellular asymm...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2008

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0808868105